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Image Search Results
Journal: Antioxidants
Article Title: Ginsenoside Rg1 Delays Chronological Aging in a Yeast Model via CDC19- and SDH2-Mediated Cellular Metabolism
doi: 10.3390/antiox12020296
Figure Lengend Snippet: Antisenescence effects of Rg1 intervention on CDC19 -overexpressing ( cdc19 OE ) and SDH2 -deficient ( sdh2Δ ) strains of S. cerevisiae . ( a ) Graphical representation of ECAR measurements over time in S. cerevisiae strain BY4742 (the parental strain; Control and Rg1) and the cdc19 OE strain. ( b ) Calculation of representative functional parameters of glycolysis from ECAR curves. “Glycolysis” indicates the ECAR when glucose was injected; “Glycolytic Capacity” indicates the ECAR when oligomycin was injected; “Glycolytic Reserve” indicates the difference between Glycolysis and Glycolytic Capacity. Hexokinase ( c ), PFK ( d ), and PGK ( e ) enzyme activities. ( f ) Growth curves of S. cerevisiae BY4742 (Control and Rg1) and cdc19 OE strains. ( g ) Graphical representation of OCR measurements over time in strains BY4742 (Control and Rg1) and sdh2Δ . ( h ) Calculation of representative functional parameters of OXPHOS from OCR curves. “Basal Respiration” indicates the OCR in the absence of oligomycin; “ATP-linked Respiration” indicates the OCR after injection of oligomycin; “Maximal Respiration” indicates the OCR after injection of FCCP. MMP ( i ) and ATP ( j ) production levels in S. cerevisiae strains BY4742 (Control and Rg1) and sdh2Δ . ( k ) Growth curves of strains BY4742 (control and Rg1) and sdh2Δ . Data are expressed as the mean ± SD; n = 3. Compared with untreated controls, * p < 0.05, ** p < 0.01, **** p < 0.0001.
Article Snippet: The
Techniques: Control, Functional Assay, Injection